abstract：PURPOSE:To evaluate the clinical features, treatment, and prognosis of patients with uveal metastasis from lung cancer. DESIGN:Retrospective chart review. PARTICIPANTS:There were 194 patients with a diagnosis of uveal metastasis from lung cancer. INTERVENTION:Radiotherapy, chemotherapy, enucleation, or observation. ...

journal_title：Ophthalmology

authors： Shah SU,Mashayekhi A,Shields CL,Walia HS,Hubbard GB 3rd,Zhang J,Shields JA

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To describe the long-term ophthalmologic outcomes of patients with methylmalonic aciduria and homocystinuria, cobalamin C type (cblC). DESIGN:Retrospective case series. PARTICIPANTS:All patients with cblC referred to the Department of Ophthalmology of the Centre Hospitalier Universitaire Sainte-Justine from...

journal_title：Ophthalmology

authors： Gizicki R,Robert MC,Gómez-López L,Orquin J,Decarie JC,Mitchell GA,Roy MS,Ospina LH

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To investigate the association between the vascular endothelial growth factor (VEGF) gene polymorphism and the response to anti-VEGF treatment for choroidal neovascularization (CNV) in highly myopic eyes. DESIGN:Retrospective cohort study. PARTICIPANTS:A total of 357 unrelated highly myopic Japanese patients ...

journal_title：Ophthalmology

authors： Miyake M,Yamashiro K,Akagi-Kurashige Y,Kumagai K,Nakata I,Nakanishi H,Oishi A,Tsujikawa A,Yamada R,Matsuda F,Yoshimura N

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To assess the effectiveness of intravitreal aflibercept in patients with neovascular age-related macular degeneration (AMD) previously resistant to treatment with other anti-vascular endothelial growth factor agents. DESIGN:Prospective, open-label, noncontrolled, registered clinical trial. PARTICIPANTS:Fort...

journal_title：Ophthalmology

authors： Chang AA,Li H,Broadhead GK,Hong T,Schlub TE,Wijeyakumar W,Zhu M

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To determine the longitudinal trends in the probability of blindness due to open-angle glaucoma (OAG) in Olmsted County, Minnesota, from 1965 to 2009. DESIGN:Retrospective, population-based cohort study. PARTICIPANTS:All residents of Olmsted County, Minnesota (aged ≥ 40 years) who were diagnosed with OAG be...

journal_title：Ophthalmology

authors： Malihi M,Moura Filho ER,Hodge DO,Sit AJ

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To determine efficacy and safety of intravitreal aflibercept in patients with neovascular age-related macular degeneration (AMD) during a second year of variable dosing after a first-year fixed-dosing period. DESIGN:Two randomized, double-masked, active-controlled, phase 3 trials. PARTICIPANTS:Two thousand fo...

journal_title：Ophthalmology

authors： Schmidt-Erfurth U,Kaiser PK,Korobelnik JF,Brown DM,Chong V,Nguyen QD,Ho AC,Ogura Y,Simader C,Jaffe GJ,Slakter JS,Yancopoulos GD,Stahl N,Vitti R,Berliner AJ,Soo Y,Anderesi M,Sowade O,Zeitz O,Norenberg C,Sandbrink R

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To investigate the rate and risk factors of developing suprachoroidal hemorrhage (SCH) after pars plana vitrectomy (PPV) and the outcomes as a result. DESIGN:Retrospective, comparative consecutive series. PARTICIPANTS:A total of 5459 patients who underwent pars plana vitrectomies over 10 years in 3 surgical c...

journal_title：Ophthalmology

authors： Chandra A,Xing W,Kadhim MR,Williamson TH

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate whether artificial tears and cold compress alone or in combination provide a treatment benefit and whether they were as effective as or could enhance topical antiallergic medication. DESIGN:Randomized, masked clinical trial. PARTICIPANTS:Eighteen subjects (mean age, 29.5±11.0 years) allergic ...

journal_title：Ophthalmology

authors： Bilkhu PS,Wolffsohn JS,Naroo SA,Robertson L,Kennedy R

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To investigate the visual outcome, pattern of discontinuation, ocular complications, and mortality of patients treated with a variable ranibizumab dosing regimen for neovascular age-related macular degeneration (AMD) for 4 years. DESIGN:Retrospective chart review supplemented with clinical examination. PART...

journal_title：Ophthalmology

authors： Rasmussen A,Bloch SB,Fuchs J,Hansen LH,Larsen M,LaCour M,Lund-Andersen H,Sander B

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To investigate the influence of the vitreomacular interface (VMI) on the functional and anatomic efficacy of ranibizumab therapy in patients with neovascular age-related macular degeneration (AMD). DESIGN:Subanalysis of a prospective, 12-month, multicenter, phase IIIb trial. PARTICIPANTS:A total of 353 treatm...

journal_title：Ophthalmology

authors： Mayr-Sponer U,Waldstein SM,Kundi M,Ritter M,Golbaz I,Heiling U,Papp A,Simader C,Schmidt-Erfurth U

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To investigate the impact of age-related change of macular and circumpapillary retinal nerve fiber layer (RNFL) measurements on evaluation of glaucoma progression. DESIGN:Prospective, longitudinal study. PARTICIPANTS:A total of 150 eyes of 90 patients with glaucoma and 72 eyes of 40 normal individuals. MET...

journal_title：Ophthalmology

authors： Leung CKS,Ye C,Weinreb RN,Yu M,Lai G,Lam DS

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:This study sought to determine the validity of self-report of prior panretinal photocoagulation (PRP) and focal photocoagulation (FP) compared with fundus photography. DESIGN:Prospective cohort study. PARTICIPANTS:One thousand three hundred sixty-three type 1 diabetic subjects from the Epidemiology of Diabete...

journal_title：Ophthalmology

authors： Grassi MA,Sun W,Gangaputra S,Cleary PA,Hubbard L,Lachin JM,Gao X,Kiss S,Barkmeier AJ,Almony A,Davis M,Klein R,Danis RP,DCCT\/EDIC Research Group.

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To provide a summary of the impact on vision of an aspheric intraocular lens (IOL) compared with a spherical IOL in cataract surgery. DESIGN:Systematic review with meta-analysis. PARTICIPANTS:Patients from published randomized controlled trials (RCTs) of cataract surgery with aspheric compared with spherical ...

journal_title：Ophthalmology

authors： Schuster AK,Tesarz J,Vossmerbaeumer U

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:To estimate payments for glaucoma care among Medicare beneficiaries from 2002 to 2009. DESIGN:Database study. PARTICIPANTS:Data from a 5% random sample of Medicare billing information from 2002 to 2009. METHODS:Medicare beneficiaries, aged 65 years or older, with both Parts A and B fee-for-service (FFS) enro...

journal_title：Ophthalmology

authors： Quigley HA,Cassard SD,Gower EW,Ramulu PY,Jampel HD,Friedman DS

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To evaluate agreement between fluorescein angiography (FA) and optical coherence tomography (OCT) results for diagnosis of macular edema in patients with uveitis. DESIGN:Multicenter cross-sectional study. PARTICIPANTS:Four hundred seventy-nine eyes with uveitis from 255 patients. METHODS:The macular status...

journal_title：Ophthalmology

authors： Kempen JH,Sugar EA,Jaffe GJ,Acharya NR,Dunn JP,Elner SG,Lightman SL,Thorne JE,Vitale AT,Altaweel MM,Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group.

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To develop a classification of parapapillary atrophy (PPA) based on its relationship with the location of Bruch's membrane (BM) termination in primary open-angle glaucoma (POAG) patients. DESIGN:Cross-sectional observational study. PARTICIPANTS:This study analyzed 161 eyes from 161 POAG patients who had tempo...

journal_title：Ophthalmology

authors： Kim M,Kim TW,Weinreb RN,Lee EJ

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To assess distribution, correlations, and prognostic effect of tumor (T), node (N), and metastasis (M) staging on relapse and survival. DESIGN:Retrospective clinical review. PARTICIPANTS:Sixty-three patients diagnosed with primary ocular adnexal lymphoma (OAL) between January 1986 and November 2011. METHODS:...

journal_title：Ophthalmology

authors： Aronow ME,Portell CA,Rybicki LA,Sweetenham JW,Singh AD

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To define and characterize a novel pre-Descemet's layer in the human cornea. DESIGN:Clinical and experimental study. PARTICIPANTS:We included 31 human donor sclerocorneal discs, including 6 controls (mean age, 77.7 years). METHODS:Air was injected into the stroma of donor whole globes (n = 4) and sclerocorne...

journal_title：Ophthalmology

authors： Dua HS,Faraj LA,Said DG,Gray T,Lowe J

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:To describe the observed frequency of oculo-auriculo-vertebral spectrum (OAVS) in patients with dermolipoma. DESIGN:Retrospective case series. PARTICIPANTS:Patients with primary presentation of ocular dermolipoma. METHODS:All patients with ocular dermolipoma or lipodermoid were identified from the authors'...

journal_title：Ophthalmology

authors： Khong JJ,Hardy TG,McNab AA

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To assess the structure of central optic disc pits (ODPs) using enhanced-depth imaging optical coherence tomography (EDI OCT) and to ascertain their clinical significance. DESIGN:Prospective, cross-sectional study. PARTICIPANTS:Patients with an ophthalmoscopically visible central ODP in either eye, irrespec...

journal_title：Ophthalmology

authors： Qayum S,Sullivan T,Park SC,Merchant K,Banik R,Liebmann JM,Ritch R

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To develop and validate a predictive model to estimate the probability of being nonadherent to topical glaucoma medications. DESIGN:Prospective cohort study. PARTICIPANTS:Patients being treated with once-daily prostaglandin eye drops. METHODS:A predictive model for nonadherence was developed from the Trava...

journal_title：Ophthalmology

authors： Chang DS,Friedman DS,Frazier T,Plyler R,Boland MV

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:To report the long-term results of corneal collagen cross-linking (CXL) in ectasia after LASIK and photorefractive keratectomy (PRK). DESIGN:Retrospective, interventional cases series. PARTICIPANTS:Twenty-six eyes of 26 patients (18 male, 8 female) with postoperative ectasia after LASIK (23 eyes) and PRK (3 e...

journal_title：Ophthalmology

authors： Richoz O,Mavrakanas N,Pajic B,Hafezi F

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:To determine the proportion of all Myocilin coding mutations responsible for advanced primary open-angle glaucoma (POAG) in early-age-at-onset individuals and to investigate the prevalence of exon 3 Myocilin mutations in advanced POAG at any age at onset in a large Australasian cohort. DESIGN:Cross-sectiona...

journal_title：Ophthalmology

authors： Souzeau E,Burdon KP,Dubowsky A,Grist S,Usher B,Fitzgerald JT,Crawford A,Hewitt AW,Goldberg I,Mills RA,Ruddle JB,Landers J,Mackey DA,Craig JE

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To evaluate the relationship between retinal sensitivity and the photoreceptor inner segment/outer segment (IS/OS) layer status in patients with diabetic macular edema (DME). DESIGN:Cross-sectional study. PARTICIPANTS:Twenty-five adult patients (37 eyes) diagnosed with DME and managed at the Wilmer Eye Instit...

journal_title：Ophthalmology

authors： Yohannan J,Bittencourt M,Sepah YJ,Hatef E,Sophie R,Moradi A,Liu H,Ibrahim M,Do DV,Coulantuoni E,Nguyen QD

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To analyze the success rate of pulsed intravenous (IV) cyclophosphamide (CyP) for noninfectious ocular inflammatory disease and to identify risk factors for failure of therapy. DESIGN:Retrospective, interventional, noncomparative cohort study. PARTICIPANTS:One hundred ten eyes of 65 patients. METHODS:Through...

journal_title：Ophthalmology

authors： Suelves AM,Arcinue CA,González-Martín JM,Kruh JN,Foster CS

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To characterize peripheral fundus autofluorescence (FAF) abnormalities in patients with age-related macular degeneration (AMD), correlate these with clinical findings, and identify risk factors associated with these FAF abnormalities. DESIGN:Clinic-based, cross-sectional study. PARTICIPANTS:A total of 119 con...

journal_title：Ophthalmology

authors： Tan CS,Heussen F,Sadda SR

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To investigate the use of swept-source optical coherence tomography (OCT) for measuring the area and degree of peripheral anterior synechia (PAS) involvement in patients with angle-closure glaucoma. DESIGN:Cross-sectional study. PARTICIPANTS:Twenty-three eyes with PAS (detected by indentation gonioscopy) fr...

journal_title：Ophthalmology

authors： Lai I,Mak H,Lai G,Yu M,Lam DS,Leung CK

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To describe visual impairment (VI) over a 20-year period and its associations with age-related eye diseases and socioeconomic factors in the Beaver Dam Eye Study. DESIGN:Population-based cohort study. PARTICIPANTS:Four thousand nine hundred twenty-six persons 43 to 86 years of age participated in the baseline...

journal_title：Ophthalmology

authors： Klein R,Lee KE,Gangnon RE,Klein BE

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:To determine the long-term reproducibility of the retinal nerve fiber layer (RNFL) thickness deviation map in glaucoma patients. DESIGN:Retrospective, longitudinal study. PARTICIPANTS:One hundred two eyes of 102 glaucoma patients. METHODS:From a total of 318 screened glaucoma patients who had undergone at ...

journal_title：Ophthalmology

authors： Roh KH,Jeoung JW,Park KH,Yoo BW,Kim DM

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To report the 4-year outcomes of corneal cross-linking (CXL) for progressive keratoconus in a population of different age groups. DESIGN:Retrospective, single-center, nonrandomized clinical study. PARTICIPANTS:Four hundred consecutive eyes treated with corneal CXL for progressive keratoconus from April 2006 t...

journal_title：Ophthalmology

authors： Vinciguerra R,Romano MR,Camesasca FI,Azzolini C,Trazza S,Morenghi E,Vinciguerra P

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To determine the impact that cataract and cataract surgery have on clinical measurements of vision, reading speed, objective mobility performance, and subjective visual functioning. DESIGN:Prospective, population-based study. PARTICIPANTS:A total of 1739 Salisbury Eye Evaluation (SEE) participants without pre...

journal_title：Ophthalmology

authors： Lee BS,Munoz BE,West SK,Gower EW

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To investigate the characteristics and prognosis of immune rejection after allogeneic cultivated limbal epithelial transplantation (CLET). DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Forty-two eyes of 41 patients undergoing allogeneic CLET for total limbal stem cell deficiency who completed...

journal_title：Ophthalmology

authors： Qi X,Xie L,Cheng J,Zhai H,Zhou Q

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To compare effective phacoemulsification time after femtosecond laser pretreatment with conventional phacoemulsification and the associated effect on visual outcomes and endothelial cell loss. DESIGN:Prospective, consecutive, single-surgeon case-control study. CONTROLS:Controls underwent phacoemulsification...

journal_title：Ophthalmology

authors： Abell RG,Kerr NM,Vote BJ

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To report treatment outcomes in malignant glaucoma. DESIGN:Retrospective case series. PARTICIPANTS:Twenty-eight eyes of 26 patients who were treated for malignant glaucoma between 1991 and 2009. METHODS:Malignant glaucoma was diagnosed based on the presence of a shallow or flat central and peripheral anterio...

journal_title：Ophthalmology

authors： Dave P,Senthil S,Rao HL,Garudadri CS

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To estimate retinal ganglion cell (RGC) losses associated with the earliest development of visual field defects in glaucoma. DESIGN:Observational cohort study. PARTICIPANTS:The study group included 53 eyes of 53 patients with suspected glaucoma who were followed as part of the Diagnostic Innovations in Glauco...

journal_title：Ophthalmology

authors： Medeiros FA,Lisboa R,Weinreb RN,Liebmann JM,Girkin C,Zangwill LM

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:To develop a clinical classification system for age-related macular degeneration (AMD). DESIGN:Evidence-based investigation, using a modified Delphi process. PARTICIPANTS:Twenty-six AMD experts, 1 neuro-ophthalmologist, 2 committee chairmen, and 1 methodologist. METHODS:Each committee member completed an o...

journal_title：Ophthalmology

authors： Ferris FL 3rd,Wilkinson CP,Bird A,Chakravarthy U,Chew E,Csaky K,Sadda SR,Beckman Initiative for Macular Research Classification Committee.

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To investigate the associations of the C2-CFB-RDBP-SKIV2L region with neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). DESIGN:Cross-sectional, case-control association study. PARTICIPANTS:A Chinese case-control group of 200 neovascular AMD patients, 233 PCV patie...

journal_title：Ophthalmology

authors： Liu K,Chen LJ,Tam PO,Shi Y,Lai TY,Liu DT,Chiang SW,Yang M,Yang Z,Pang CP

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To determine the outcome of a reduced amount of medial rectus (MR) muscle recession in esotropes with cerebral palsy (CP) and to compare the surgical response with that of normal controls. DESIGN:Retrospective cohort study. PARTICIPANTS:Thirty esotropes with CP and 60 age-matched esotropes without CP who unde...

journal_title：Ophthalmology

authors： Ma DJ,Yang HK,Hwang JM

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To identify effective methods to increase the number of cataract surgeries in a rural setting in Pucheng County of Shaanxi Province, northwestern China. DESIGN:Community-based randomized interventional study. PARTICIPANTS:Four hundred thirty-two patients 50 years of age or older with operable cataract who had...

journal_title：Ophthalmology

authors： Zhang XJ,Liang YB,Liu YP,Jhanji V,Musch DC,Peng Y,Zheng CR,Zhang HX,Chen P,Tang X,Lam DS

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To characterize retinal pigment epithelial (RPE) cell loss as evidenced by autofluorescence imaging in patients with neovascular age-related macular degeneration (AMD). DESIGN:Retrospective cohort study. PARTICIPANTS:There were 162 eyes of 116 consecutive patients with neovascular AMD examined in a retinal pr...

journal_title：Ophthalmology

authors： Kumar N,Mrejen S,Fung AT,Marsiglia M,Loh BK,Spaide RF

更新日期：2013-02-01 00:00:00